abstract：:The subthalamic nucleus (STN) is the primary target for the chronic deep brain stimulation treatment of Parkinson's disease. STN neurons exhibit a variety of characteristic properties that may play a key role in the overall population response to deep brain stimulation. Neuroinformatics techniques, in particular compu...

journal_title：Expert review of medical devices

authors： Gillies A,Willshaw D

更新日期：2007-09-01 00:00:00

abstract：:Future viral outbreaks are a major threat to societal and economic development throughout the world. A rapid, sensitive and easy-to-use test for viral infections is essential to prevent and control such viral pandemics. Furthermore, a compact, portable device is potentially very useful in remote or developing regions ...

journal_title：Expert review of medical devices

authors： Ymeti A,Subramaniam V,Beumer TA,Kanger JS

更新日期：2007-07-01 00:00:00

abstract：:Atrial fibrillation (AF), the most common arrhythmia, has a major impact on both patient morbidity and healthcare economics. Hospital admissions due to AF have risen by two-thirds in the last 20 years. This is due mainly to an aging population and an increasing prevalence of chronic heart disease. Strategies for the m...

journal_title：Expert review of medical devices

authors： Mischke K,Schimpf T,Knackstedt C,Hanrath P,Schauerte P

更新日期：2007-07-01 00:00:00

abstract：:In this review, surface modification of implant devices by immobilization of biological molecules is discussed. A brief introduction to the development of biomolecular surface science is presented, followed by a review of current activities in selected fields. Bone-contacting devices and some cardiovascular implant de...

journal_title：Expert review of medical devices

authors： Morra M

更新日期：2007-05-01 00:00:00

abstract：:Nanotechnology is increasingly applied to the field of medicine, particularly for the treatment of cancer. In this regard, gold nanoparticles can mediate hyperthermia induction and kill tumor cells upon laser irradiation, thereby functioning as a 'thermal scalpel'. Recent developments in gold nanoparticle design have ...

journal_title：Expert review of medical devices

authors： Everts M

更新日期：2007-03-01 00:00:00

abstract：:Glaucoma is a leading cause of blindness worldwide. Currently, topical drops are the mainstay of treatment for patients who suffer from this chronic disease. Adherence to topical therapy is known to be affected by forgetfulness, frequent dosing requirements and physical limitations. Dosing and adherence aids are desig...

journal_title：Expert review of medical devices

authors： Kahook MY

更新日期：2007-03-01 00:00:00

abstract：:This article investigates various neural machine interfaces for voluntary control of externally powered upper-limb prostheses. Epidemiology of upper limb amputation, as well as prescription and follow-up studies of externally powered upper-limb prostheses are discussed. The use of electromyographic interfaces and peri...

journal_title：Expert review of medical devices

authors： Ohnishi K,Weir RF,Kuiken TA

更新日期：2007-01-01 00:00:00

abstract：:Total hip resurfacing has long been conceptually attractive to both surgeons and patients. However, historically it has been plagued by limited durability and marked acetabular bone loss. The recent development of wear-resistant bearings, such as metal-on-metal, has led to renewed interest in hip resurfacing in the or...

journal_title：Expert review of medical devices

authors： Moroni A,Cadossi M,Bellenghi C,Romagnoli M,Bevoni R,Giannini S

更新日期：2006-11-01 00:00:00

abstract：:With advances in endoscopic imaging tools, it is becoming increasingly possible to find, assess and treat numerous gastrointestinal (GI) pathologies at the time of endoscopy. This article focuses on the newly developed Pentax confocal endomicroscope that enables in vivo microscopic imaging of the upper and lower GI tr...

journal_title：Expert review of medical devices

authors： Polglase AL,McLaren WJ,Delaney PM

更新日期：2006-09-01 00:00:00

abstract：:Surgeons often encounter the challenge of treating acquired abdominal wall defects following abdominal surgery. The current standard of practice is to repair most defects using permanent synthetic mesh material. Mesh augments the strength of the weakened abdominal wall fascia and enables the hernia repair to be perfor...

journal_title：Expert review of medical devices

authors： Bellows CF,Alder A,Helton WS

更新日期：2006-09-01 00:00:00

abstract：:Cellular magnetic resonance imaging (CMRI) allows for the tracking of the temporal and spatial migration of cells labeled with MR contrast agents within organs and tissues. This rapidly growing area of experimental research has the potential of translating from bench to bedside and may be used in conjunction with cell...

journal_title：Expert review of medical devices

authors： Arbab AS,Liu W,Frank JA

更新日期：2006-07-01 00:00:00

abstract：:The Amplatzer Duct Occluder is a novel device designed to allow for the transcatheter closure of virtually all sized patent ductus arteriosuses. Prior technologies have been cumbersome and challenging to deploy with somewhat less than ideal closure rates associated with their use. This article summarizes the present k...

journal_title：Expert review of medical devices

authors： Pass RH

更新日期：2006-05-01 00:00:00

abstract：:Ureteral stents are used in a variety of urological diseases and procedures. The majority of patients with indwelling ureteral stents experience bothersome symptoms and are at increased risk for urinary tract infection. Stent encrustation and the associated complications can also result in significant patient morbidit...

journal_title：Expert review of medical devices

authors： Chew BH,Duvdevani M,Denstedt JD

更新日期：2006-05-01 00:00:00

abstract：:Transmyocardial revascularization, using the US FDA-approved holmium: yttrium-aluminum-garnet (Ho:YAG) laser system, is a surgical option for patients with debilitating angina caused by diffuse coronary artery disease in areas of the heart not amenable to complete revascularization using conventional treatments. Incre...

journal_title：Expert review of medical devices

authors： Allen KB

更新日期：2006-03-01 00:00:00

abstract：:To reduce the toxic effects, related clinical problems and complications such as bleeding disorders associated with systemic anticoagulation, it has been hypothesized that by coating the surfaces of medical devices, such as stents, bypass grafts, extracorporeal circuits, guide wires and catheters, there will be a sign...

journal_title：Expert review of medical devices

authors： Conn G,Kidane AG,Punshon G,Kannan RY,Hamilton G,Seifalian AM

更新日期：2006-03-01 00:00:00

abstract：:This review focuses on the expanding role for biomaterials and polymer scaffolds in liver tissue engineering. Studies are subdivided into in vitro and in vivo approaches. The in vitro section of the review discusses the challenges specific to liver tissue engineering, and how the choice of scaffold and its structure i...

journal_title：Expert review of medical devices

authors： Hammond JS,Beckingham IJ,Shakesheff KM

更新日期：2006-01-01 00:00:00

abstract：:For decades, electroactive polymers received relatively little attention due to their limited actuation capability. However, in the last 15 years, a series of electroactive polymer materials have emerged that produce a significant shape or size change in response to electrical stimulation. These materials have the clo...

journal_title：Expert review of medical devices

authors： Bar-Cohen Y

更新日期：2005-11-01 00:00:00

abstract：:Capsule endoscopy is a major breakthrough in gastrointestinal endoscopy and is a first-line tool to detect abnormalities of the small bowel, in up to 50% of patients, intestinal disorders are not associated with any physical findings or positive tests. Indications, yield and impact on patient management of this method...

journal_title：Expert review of medical devices

authors： Pennazio M

更新日期：2005-09-01 00:00:00

abstract：:Deep brain stimulation has emerged rapidly as an effective therapy for movement disorders. Deep brain stimulation includes an implanted brain electrode and a pacemaker-like implanted pulse generator. The clinical application of deep brain stimulation proceeded in the absence of clear understandings of its mechanisms o...

journal_title：Expert review of medical devices

authors： Grill WM

更新日期：2005-07-01 00:00:00

abstract：:In addition to conventional treatment modalities (mechanical and chemical), the use of lasers has been increasingly proposed for the treatment of periodontal and peri-implant infections (i.e., cleaning and detoxification of implant surfaces). Preliminary results from basic studies have pointed to the high potential of...

journal_title：Expert review of medical devices

authors： Sculean A,Schwarz F,Becker J

更新日期：2005-05-01 00:00:00

abstract：:Radiosurgery is the application of radiation therapy in an extremely precise manner. These techniques apply large bioequivalent doses of radiation to a small area in order to destroy tumor cells, while sparing surrounding normal tissues. Radiosurgery has been available for intracranial abnormalities since the 1950s bu...

journal_title：Expert review of medical devices

authors： Welch WC,Gerszten PC

更新日期：2005-03-01 00:00:00

abstract：:Prosthetic heart valves are routinely used for replacing diseased natural heart valves. Even today, after five decades of prosthetic heart valve development, in the authors opinion the main problem associated with these valves is the risk of thromboembolic complications caused by unnatural hemodynamics. Further growin...

journal_title：Expert review of medical devices

authors： Goubergrits L,Affeld K,Kertzscher U

更新日期：2005-01-01 00:00:00

abstract：:Although implanted for over 40 years, finger prostheses have failed to match the success achieved by artificial hip and knee prostheses, despite a myriad of designs having been proposed and implanted. This article looks at the currently available designs of metacarpophalangeal prosthesis, both single-piece and multico...

journal_title：Expert review of medical devices

authors： Joyce TJ

更新日期：2004-11-01 00:00:00

abstract：:Drug-eluting stents are a major breakthrough in cardiology, with the Cypher (Cordis Corporation) and Taxus (Boston Scientific) stents preventing 60-70% of repeat coronary revascularizations, compared with bare metal stents. Both evidence- and risk-based application of drug-eluting stents is expected to create relevant...

journal_title：Expert review of medical devices

authors： Marchetti M

更新日期：2004-09-01 00:00:00